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The citric acid cycle is the major route for aerobic processes in animal tissues. It was discovered in 1937 and is also known as the Krebs cycle or tri-cycle (Krebs cycle). This is a series of reactions that are important to living cells. They offer a complete oxidation of C2 units or acetyl-CoA derived from fats, carbohydrates and lipids. The oxidation process is carbon dioxide and water. The citric acid cycle is a series of reactions catalyzed by enzymes which take place in the context of cellular respiration. Occurs just in the matrix of mitochondria present in a cell. It is part of the metabolic pathway which produces a fuel for use in the human body.

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As already mentioned citric acid cycle is complete breakdown of food into energy from energy-rich molecules, which are final products of the reaction to generate. The body is produced, the energy from these molecules as fuel. The acetyl-coenzyme, which is produced by the degradation of sugars, fatty acids and amino acids, reacting with oxaloacetic acid to produce more citric acid, which is again converted to oxaloacetic acid, after a series of chemical reactions catalyzed by enzymes. Throughout the chemical conversion process, carbon dioxide and water are produced in different stages and ATP molecules are also formed, which are reservoirs of energy.

Steps involved in chemical reactions

• The citric acid cycle begins when the coenzyme A transfers the group C 2-acetyl compound 4 to oxaloacetate-citrate and forming a carbon molecule to 6 carbons.

• citrate is then rearranged to form an isomeric form (isomer is a molecule having the same number and type of atoms than the other molecule, but the structure is different.). It forms an isocitrate.

• The 6-carbon isocitrate is then oxidized, and one molecule of carbon dioxide is removed by the preparation of the molecule ketuglutarate 5-alpha-carbon. During this process of NAD to NADH oxidation (an equivalent of 3 ATP) + H converted

• then coenzyme A is removed, so that the succinate can be produced. The energy that is released is used to guanosine triphosphate or GTP to guanosine diphosphate or GDP. The GTP is then converted to ADP.

• Then, succinate, which was prepared in the last step is converted to fumarate represented by the oxidation process. During this process, FAD is reduced to FADH2.

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• malate fumarate formed when water is added. Malate is then produced by the oxidation process and oxaloacetate, the starting compound of the citric acid cycle. During this process reduces the oxidation of NAD + to NADH + H

This cycle is often referred to as amphibole, as they cover two catabolism and anabolism. The cycle occurs when the body is in need of energy. In addition to providing energy for the body, but also provides metabolic intermediates for biosynthetic processes.